慢性阻塞性肺病急性加重期应用“三升袋”全营养液的疗效评估

Clinical effect evaluation of TNA all-in-One in patient with chronic obstrutie pulmonary diease

目的探讨使用"三升袋(TNA全合一)"营养支持对慢性阻塞性肺病(COPD)急性加重期合并营养不良的疗效及相关指标评估。方法慢性阻塞性肺病(COPD)急性加重期合并营养不良患者40例,随机分为"三升袋"组及对照组,给予为期2周的"三升袋"营养支持。结果①临床疗效":三升袋"组有效率为92.8%,对照组65.7%,P<0.05。②体重指数及MRC指数检查:"三升袋"组体重指数显著增加(P<0.05),MRC级别显著降低(P<0.05),而对照组体重指数及MRC指数无明显变化(P>0.05)。③生化指标:"三升袋"组血清铁蛋白、血清白蛋白显著增加(P<0.05),对照组血清铁蛋白、血清白蛋白无明显变化(P>0.05)。③血气及肺功能:"三升袋"组的PaO2、PaCO2、FVC及FEV1/FVC有明显改善(P<0.05),对照组上述指标无显著性改变(P>0.05)。结论 "三升袋"营养支持可提高COPD急性加重期患者临床疗效,改善相关指标。

【Objective】 To explore the effect of TNA all-in-One nutritional support in treatment of patient with chonic obstructive pulmonary disease（COPD）.【Methods】40 patients with AECOPD were randomly divided into two groups： TNA group and control group.They were observed for two weeks after TNA all-in-One nutritional sup-port.【Results】Clinical effect： effective rate of TNA all-in-One group was 92.8%,control group was 65.7%,P 0.05.body mass index（BMI） and Medical Research Council（MRC） chronic dyspnoea scale： BMI in TNA all-in-One group was significantly increased（P 0.05）,but didn＇t significantly change in control group（P 0.05）.MRC in TNA all-in-One group was significantly degrade（P 0.05）,but didn＇t significantly change in control group（P 0.05）.Bio-chemical test index：blood serum albumin and serum ferritin in TNA all-in-One group were significantly increased（P 0.05）,but didn＇t significantly change in control group（P 0.05）.Arterial blood gas and measurements of pulmonary function： PaO2,PaCO2,FVC,FEV1/FVC in TNA all-in-One group were significantly increased（P 0.05）,but didn＇t significantly change in control group（P 0.05）.【Conclusion】TNA all-in-One nutritional support can improve cor-related index,and enhance clinical effect in patient during acute exacerbation of COPD.