宫颈癌筛查研究进展

New Progress in Cervical Cancer Screening

宫颈癌是女性生殖系统最常见的恶性肿瘤,是世界卫生组织唯一建议在世界范围内开展筛查的恶性肿瘤,各个国家和地区宫颈癌筛查方案不尽相同,目前的筛查方案主要有:巴氏涂片法、液基细胞学检查、人乳头瘤病毒DNA(HPV-DNA)检测法及肉眼检查等。推行合理筛查方案对各个地区的宫颈癌及其癌前病变的预防工作极为重要。目前宫颈癌筛查也存在一些问题,如筛查人群、筛查间隔时间和筛查方案等,就目前宫颈癌筛查存在的问题及各个方案的应用及联合应用的可行性、优缺点和新进展进行论述。

Cervical cancer is one of the most common malignant tumors in gynecology,which is the only cancer recommended by The World Health Organization to start screening throughout the world.The screening strategy is different from countries.The current methods are Pap smear,liquid-based cytology,HPV-DNA testing,visual inspection （VIA）,visual inspection with Lugol＇s iodine（VILI） and so on.It is considerable to apply the reasonable strategy in different districts.Still several problems exist,such as screening crowd,screening interval and screening method and so on.This paper reviews these exist problems and the research progress in the current cervical screening methods and the feasibility of the combination of different screening methods.