162例小儿紫癜性肾炎肾脏病理与中医辨证关系探讨

Discussion on Relationship Between the TCM Differentiation and the Renal Pathology in 162 Cases with Anaphylactoid Purpura Nephritis

目的探讨小儿过敏性紫癜性肾炎肾脏病理与中医辨证关系,以指导临床。方法收集162例过敏性紫癜性肾炎患儿肾活检资料,分析病理类型分布和中医证型分布。结果前者以系膜增生为主(占68.5%),后者以脾肾阳虚为多(占55.6%),随病理类型的加重,表现为虚证的例数增多。此外,表现为血瘀证的并不少见,与临床实际相符。结论临床对紫癜性肾炎患儿进行辨证时,可结合病理类型来进行。

Objective： To explore the relationship between the TCM differentiation and the renal pathology of children with anaphylactoid purpura.Methods： Renal biopsies materials in 162 cases were collected to analyze the distribution of pathological types and syndromes of TCM.Results： The type of membrane hyperplasia is the main pathological type（68.5%） and the pattern of spleen and kidney yang deficiency is the most common syndrome（55.6%）.With the development of pathological type,the cases of deficiency were increasing.Moreover,the cases with blood stasis syndromes were not uncommon,but these results were consist with the clinical reality.Conclusion： The pathology type could be used as a reference in the differentiation of the anaphylactoid purpura nephritis.