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罗库溴铵靶控输注用于老年患者系统性能评价 被引量:3

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摘要 目的 评估内嵌Szenohradszkay参数的罗库溴铵靶控输注(TCI)系统用于老年患者的系统性能.方法 20例ASAⅡ级择期全麻手术老年患者,使用Szenohradszkay参数,靶控输注罗库溴铵,间断采集动脉血,应用液相色谱-质谱法(LCMS)测定罗库溴铵血药浓度.采用偏离度(MDPE)、精确度(MDAPE)、摆动度(Wobble)和分散度(divergence)评价靶控输注系统准确性.结果 罗库溴铵输注期间及输注停止后,各时点实测浓度高于靶浓度(P〈0.05).TCI期间系统的偏离度为14.55%、精确度为28.86%、摆动度为14.82%、分散度为-0.4%/h;TCI停止后系统的偏离度为12.79%、精确度为21.63%、摆动度为8.33%、分散度为-0.30%/h.结论 Szenohradszkay参数可用于老年患者靶控输注罗库溴铵,系统的偏离度、精确度符合系统性能的要求.
出处 《中国医师杂志》 CAS 2010年第10期1426-1428,共3页 Journal of Chinese Physician
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