期刊文献+

隆突性皮肤纤维肉瘤的诊断治疗与研究进展 被引量:1

Advance of Diagnosis and Treatment in Dermatofibrosarcoma Protuberans
下载PDF
导出
摘要 目的探讨隆突性皮肤纤维肉瘤的临床特点和治疗方法。方法回顾性分析2003~2009年,在福建省肿瘤医院接受治疗且资料完整的49例隆突性皮肤纤维肉瘤临床诊治过程。结果 49例隆突性皮肤纤维肉瘤中,行扩大切除术45例,扩大切除加植皮或转移皮瓣修补术18例,术前放疗1例。全组病例复发率为8.16%,2例死于肿瘤转移。结论隆突性皮肤纤维肉瘤是皮肤低度恶性肿瘤,复发率较高,首次治疗时彻底切除为关键。外科手术是其主要的治疗方法。 Objective To investigate the clinical feature and the therapeutic methods of dermatofibrosarcoma protuberans(DFSP).Methods We performed a retrospective analysis of the records of 49 patients with DFSP who were in hospital at Fujian Provincial Tumor Hospital.Results In all 49 patients,45 patients underwent wide excision,18 patients underwent wide excision plus skin grafting or local flap grafting,1 patient received radiotherapy before surgical operation.The local recurrence rate was 8.16%.2 patients died of tumor metastasis.Conclusion DFSP has high recurrence rate,it should be treated as a soft tissue tumor with low malignancy.Surgical operation is the optimal treatment and radical excision is the most important method in the first treatment.
出处 《黑龙江医学》 2010年第10期734-736,共3页 Heilongjiang Medical Journal
关键词 广泛切除 隆突性皮肤纤维肉瘤 复发 Dermatofibrosarcoma protuberans(DFSP) Recurrence Wide excision
  • 相关文献

参考文献10

  • 1Amaud E J,Perrault M,Revol M,et al.Surgical treatment of dermatofibrosarcoma protuberans[J].Plast ReconstrSurg,1997,100(4):884-895.
  • 2Rutgers F M,Weiss S W.Fibrohistiocytic tumor[M].st.Louis:Mosby,1995:325-349.
  • 3Hass R L,Keus R B,Loftus B M,et al.The role of Radiotherapy in the local management of Dermatofibrosarcoma protuberans[J].Eur J Cancer,1997,33(7):1 055.
  • 4Farma J M,Ammori J B,Zager J S,et al.Dermatofibrosarcoma Protuberans:How Wide Should We Resect[J].Ann Surg Oncol,2010,3:31.
  • 5Paradisi A,Abeni D,Rusciani A,et al.Dermatofibrosarcoma protuberans:wide local excision vs.Mohs micrographic surgery[J].Caner Treatment Reviews,2009,34(8):728-736.
  • 6Nelson R A,Arlette J P.Mohs micrographic surgery and dermatofibrosarcoma protuberans:a multidisciplinary approach in 44 patients[J].Ann Plast Surg,2008,60(6):667-672.
  • 7Fattoruso S I,Visca P,Lopez M.Molecular approach in the treatment of dermatofibrosarcoma protuberans[J].Clin Ter,2008,159(5):361-367.
  • 8Mattox A K,Mehta A I,Grossi P M,et al.Response of malignant scalp dermatofibrosarcoma to presurgical targeted growth factor inhibition[J].J Neurosurg,2009,8:14.
  • 9Han A,Chen E H,Niedt G,et al.Neoadjuvant imatinib therapy for dermatofibrosarcoma protuberans[J].Arch Dermatol,2009,145(7):792-796.
  • 10Meissner M,k(o)níg V,Hrgovic I,et al.Human leucocyte antigen class Ⅰand class Ⅱ antigen expression in malignant fibrous histiocytoma,fibrosarcoma and dermatofibrosarcoma protuberans is significantly downregulated[J].J Eur Acad Dermatol Venereol,2010,3:23.

同被引文献10

  • 1沈镇宙,师英强.肿瘤外科手术学.2版.南京:江苏科学技术出版社,2008:171.
  • 2Kamiya T, Saga K, Kaneko R, et al. Late local recurrence of dermatofibrosarcoma protuberans in the skin of female breast. WorldJ Surg Oncol,2010,8(48): 1-5.
  • 3Yukiko K, Maho K, Nahomi N, et al. Dermatofibrosarcoma protuberans , indication of color Doppler Sonograghy imaging for diagnosis. Rinsho Derma,2006,48(12) :1752-1753.
  • 4Kau T, Lesnik G, Arnold G, et al. Sonography of dermatofibrosarcoma protuberans of the groin,J. Clin Ultrasound, 2008, 36 (8) :520-522.
  • 5Kim M, Kim KS, Han H, et al. Fibrosarcomatous transformation in dermatofibrosarcoma protuberans of the breast: a case report.J Clin Ultra,2009,37(7) :420-423.
  • 6回允中主译.外科病理学.9版.北京:北京大学医学出版社,2006:2256.
  • 7Lee SJ, Mahoney MC, Shaughnessy E. Dermatofibrosarcoma protuherrans of the breast: imaging featrees and review of the literature. AJR, 2009,193(1) : 64-69.
  • 8Shin YR, KimJY, Sung MS, et al. Sonographic findings of dermatofibrosarcoma protuberans with pathologic correlation.J Ultrasound Med,2008,27(2) :269-274.
  • 9练慧斌,姚刚,周芳,马来祥,陈默轩,章宏伟.36例隆突性皮肤纤维肉瘤临床诊疗分析[J].南京医科大学学报(自然科学版),2009,29(8):1181-1184. 被引量:15
  • 10何明媛.隆突性皮肤纤维肉瘤16例临床病理分析[J].临床与实验病理学杂志,2012,28(5):559-561. 被引量:13

引证文献1

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部