摘要
甘草酸对内毒素、卡拉胶、体外循环等因素诱发的急性肺损伤均具有良好的保护作用,可能是通过类激素样抗炎作用、抗纤维化、免疫调节以及抗氧化作用等机制发挥作用.因其疗效显著,不良反应小,甘草酸有可能成为将来临床防治急性肺损伤的策略之一.
Glycyrrhizin has a protective effect on acute lung injury induced by lipopolysaccharide,carrageenan or cardiopulmonary bypass, maybe play a role through hormone-like anti-inflammation,anti-fibrosis, immune regulation and antioxidation. Because of its significant therapeutic effect,lower side effects,glycyrrhizic could be one of the strategies for the prevention and treatment of acute lung injury in the future.
出处
《国际呼吸杂志》
2010年第20期1257-1260,共4页
International Journal of Respiration
基金
广西教育厅科研课题资助项目（200710LX069）
广西卫生厅重点科研课题资助项目（2010）
关键词
急性肺损伤
甘草酸
治疗
Acute lung injury
Glycyrrhizin
Therapy
