期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

N端B型钠尿肽前体对急诊患者呼吸困难鉴别诊断的价值 被引量：1

Diagnostic Value of NT-proBNP Levels in Emergency Patients with Dyspnea
原文传递
导出
摘要 目的研究血浆N端B型钠尿肽前体(NT-proBNP)水平对急诊患者呼吸困难鉴别诊断意义。方法对我院急诊科呼吸困难患者,检测血浆NT-proBNP含量,并进行超声心动图检查,比较心源性和肺源性呼吸困难患者血浆NT-proBNP水平的差异。结果心源性呼吸困难组和肺源性呼吸困难组血浆NT-proBNP分别为(471.40±190.99)pg/mL和(84.77±24.17)pg/ml(P<0.01);心源性呼吸困难组血浆NT-proBNP与左室射血分数呈负相关(r=-0.82,P<0.01)。结论血浆NT-proBNP对心源性呼吸困难和肺源性呼吸困难的鉴别诊断有重要意义。 Objective To study the diagnostic value of plasma NT-proBNP levels determination in emergency patients with dyspnea.Methods Plasma NT-proBNP levels and echocardiography were measured in 115 emergency patients with dyspnea,and plasma NT-proBNP levels and left ventricular ejection fraction（LVEF）were compared between 62cardiac dyspnea patients and 53 pulmonary dyspnea patients.Results The NT-proBNP levels of cardiac dyspnea group and pulmonary dyspnea group were（471.40±190.99）pg/ml and（84.77±24.17）pg/ml respectively.There was negative correlation between NT-proBNP levels and LVEF among cardiac dyspnea（r=-0.82,P〈0.01）.Conclusion The plasma BNP level has important significance in differential diagnosis in emergency patients with dyspnea.
作者 高振芳
机构地区 河南省焦作市人民医院急诊科
出处 《医药论坛杂志》 2010年第17期50-51,53,共3页 Journal of Medical Forum
关键词 N端B型钠尿肽前体 呼吸困难 鉴别诊断 NT - proBNP Dyspnea Differential diagnosis
分类号 R563 [医药卫生—呼吸系统]
  • 相关文献

参考文献6

  • 1张海峰,席修明,赵丽.B型钠尿肽对急性呼吸困难病因诊断的临床意义[J].中国急救医学,2008,28(9):781-784. 被引量：31
  • 2Ellis R, David G, Samson WK. Natriuretic peptides [ J ]. N Engl J Med, 1998,339 (5) :321-328.
  • 3Fonseca C, Sarmento PM, Minez A, et al. Comparative value of BNP and NT - proBNP in diagnosis of heart failure[ J ]. Rev Port Cardiol, 2004,23 ( 7-8 ) : 979-991.
  • 4廖茂良,庞宝强,范东波.血清BNP检测在CHF中的临床应用分析[J].放射免疫学杂志,2009,22(2):183-184. 被引量：2
  • 5Ang DS, Kong CF, KaoMp,et al. Serial bedside B - type natriuretic peptide strongly predicts prognosis in acute coronary syndrome independent of echocardiographic abnormalities [ J ]. Am Heart J, 2009,158 ( 1 ) : 133-140.
  • 6Mueller T, Gegenhuber A, Poelz W, et al. Biochemical diagnosis of impaired left ventrieular ejection fraction - comparison of the diagnostic accuracy of brain natriuretic peptide (BNP) and amino terminal proBNP ( NT - proBNP) [ J ]. Clin Chem Lab Med, 2004,42 ( 2 ) : 159- 263.

二级参考文献14

  • 1蔡洪流,方强.血浆B型利钠肽浓度对心力衰竭诊断及预后判断的作用[J].中华急诊医学杂志,2006,15(9):816-819. 被引量：23
  • 2卜法芹.AMI患者血浆脑钠肽水平测定及其与左室重构的关系[J].山东医药,2007,47(2):45-46. 被引量：12
  • 3Salomon P, et al. Plasma levels of brain natriuretic peplide, cyclic3' 5 ' -guanosine monophosphate, endothelin - 1 and noradrenaline in patients with chronic congestive heart failure. Pol Arch Med Wewn, 2003; 109(1): 43.
  • 4Logeart D, Sandubray C, Beyne P, et al. Comparative value of Doppler echocardiography and B -type natriuretic peptide in the etiologic diagnosis of acute dyspnea [ J]. J Am Coil Cardiol, 2002, 40(10) :1794 - 1800.
  • 5O'Neill JO, Bott - silverman CE, McRae AT 3rd, et al. B - type natriuetie peptide levels are not a surrogate marker for invasive hemodynamics during management of patients with severe heart failure [J]. Am Heart J,2005, 149(2) :363 -369.
  • 6Langenickel T, Pagel I, Hohnel K, et al. Differential regulation of cardiac ANP and BNP mRNA in different stages of experimental heart failure [J]. Am J Physiol Heart Circ Physiol, 2000, 278:H1500 -1506.
  • 7Knudsen CW, Omland T, Clopton P, et al. Diagnostic value of B - type natriuretie peptide and chest radiographic findings in patients with acute dyspnea [J]. Am J Med, 2004, 116(6) :363 -368.
  • 8Maisel AS, Krishnaswarny P, Nowak RM, et al. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure [J]. N Engl J Med, 2002, 347(3) :161 - 167.
  • 9陈文斌,王友赤.诊断学[M].第五版.北京:人民卫生出版社,2001:28-28.
  • 10Knudsen CW, Riis JS, Finsen AV, et al. Diagnostic value of a rapid test for B - type natriuretic peptide in patients presenting with acute dyspnea: effect of age and gender [J]. Eur J Heart Fail, 2004, 6:5 -62.

共引文献30

同被引文献8

  • 1Writing Committee. ACC/AHA2005 Guideline Update for the Diag- nosis and Management of Chronic Heart Failure in the Adult [ J ]. Circulation,2005,112(4) : 154-235.
  • 2Januzzi JL, Comargo CA, Anwaruddin S, et al. The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study[ J]. Am J Cardiol,2005 ,95 :948 - 954.
  • 3Diekstein K, Cohen-Solal A, Filippatos G, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008:The task force for the diagnosis and treatment of acute and chronic hear failure 2008 of the european society of cardiology. De- veloped in eollaboation with the hear failure association of the ESC (HFA) and endorsed by the european society of intensive care med- icine (ESJCM) [ J ]. Ear Hear J. 2008.29:2388 - 2442.
  • 4Pemberton C, Johnson M, Yandle T, et al. Deconvolution analysis of cardiac natriuretic peptides during acute volume overload [ J ]. Hypertension ,2001,36:355.
  • 5Ang DS, Kong CF, Kao Mp, et al. Serial bedside B-type natriuretic peptide strongly predicts prognosis in acute coronary syndrome inde- pendent of echocardigraphic abnormalities [ J ]. Am Heart J,2009, 158 (1) :133 -140.
  • 6张海峰,席修明,赵丽.B型钠尿肽对急性呼吸困难病因诊断的临床意义[J].中国急救医学,2008,28(9):781-784. 被引量：31
  • 7夏思良,周建松.NT-proBNP在慢性心力衰竭中的临床应用[J].心血管病学进展,2008,29(5):801-805. 被引量：12
  • 8王燕,汤明荣.272例心功能不全患者NT-proBNP检测结果的临床分析[J].放射免疫学杂志,2011,24(1):80-81. 被引量：4

引证文献1

二级引证文献7

医药论坛杂志
2010年 第17期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部