摘要
以雄性泥鳅作为模型动物,采用半静水式暴露体系,研究了镉(Cd)在泥鳅体内的富集分布以及17β-雌二醇(E2)对Cd富集分布的影响。研究结果显示,肾脏、肝脏、肠和鳃是Cd在雄性泥鳅体内的主要富集器官,且Cd的富集量呈现明显的时间-效应和剂量-效应关系。肌肉、骨头和性腺中Cd的富集量却很低。并且,E2的共同暴露或预暴露并没有改变Cd的主要富集器官。
The effect of the tissue accumulation and distribution of cadmium （Cd） in male Chinese loaches and of 17β-estradiol （E2） on the distribution of Cd were investigated via using semi-static waterborne exposure system. The results demonstrated that kidney,liver,intestine,and gills were the main targets for Cd accumulation in male Chinese loaches,and Cd bioaccumulation showed an obvious time- and dose- dependent relationship. Little amounts of Cd were accumulated in muscle,bone,and gonad. In addition,the co-exposure or pretreatment with E2 did not change the main target for Cd accumulation.
出处
《化学通报》
CAS
CSCD
北大核心
2010年第10期932-937,共6页
Chemistry
基金
国家自然科学基金项目(20905007)资助
关键词
富集
镉
泥鳅
分布
17Β-雌二醇
Accumulation
Cadmium
Chinese Loach
Distribution
17β-estradiol
