南海二叉黑角珊瑚化学成分研究

Study on the Chemical Constituents of Antipathes dichotoma

目的:研究南海二叉黑角珊瑚Antipathes dichotoma Pallas的化学成分。方法:利用反复硅胶柱色谱对化合物进行分离纯化,通过波谱分析方法,结合文献对照,鉴定化合物的结构。结果:从南海二叉黑角珊瑚提取物中分离得到9个化合物,分别为:胆甾醇(Ⅰ)、3-羟基-5-烯-麦角甾醇(Ⅱ)、3-羟基-4-甲基-麦角甾醇(Ⅲ)、对羟基苯甲酸甲酯(Ⅳ)、3,4-二羟基苯甲醛(Ⅴ)、4-羟基-3-甲氧基苯甲醛(Ⅵ)、咖啡酸(Ⅶ)、鲨甘醇(Ⅷ)、胸腺嘧啶(Ⅸ)。结论:化合物Ⅱ～Ⅶ均为首次从二叉黑角珊瑚中分离得到。

Objective： To investigate the chemical constituents of Antipathes dichotoma.Methods：The compounds were isolated and purified by column chromatography on silica gel and their structures were identified by spectral analyses and comparison with literatures.Results： Nine compounds were obtained from A.dichotam and characterized as cholesterol（Ⅰ）,ergosta-5-ene-3-ol（Ⅱ）,4-methyl-ergostatrien-3-ol（Ⅲ）,p-hydroxybenzoate（Ⅳ）,3,4-dihydroxybenzaldehyde（Ⅴ）,vanillin（Ⅵ）,caffeic acid（Ⅶ）,batyl alcohol（Ⅷ）,and theymine（Ⅸ）.Conclusion ：Compounds Ⅱ～Ⅶ are obtained from Antipathes dichotoma for the first time.