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创伤后应激障碍患者下丘脑-垂体-肾上腺轴系统研究进展 被引量：1

The new progress in the study of HPA axis activity in PTSD
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摘要 创伤后应激障碍（Post-traumatic stress disorder,PTSD）是一种严重的应激相关障碍,是机体经历严重创伤事件后延迟出现的精神障碍,其临床表现以重复创伤性体验为特征,伴有情绪的易激惹和回避行为等,国外有调查显示其终身患病率约为7.8%[1].下丘脑-垂体-肾上腺（Hypothalamic pituitary adrenal,HPA）轴在调节人体功能中发挥着重要的作用,也通过负反馈抑制调节神经,内分泌,免疫系统功能.研究显示PTSD患者存在HPA轴功能异常,本文主要就PTSD患者HPA轴研究进展进行综述.
作者 陆邵佳 李凌江
机构地区 中南大学湘雅二医院精神卫生研究所
出处 《神经疾病与精神卫生》 2010年第4期406-408,共3页 Journal of Neuroscience and Mental Health
关键词 创伤后应激障碍 HPA轴 PTSD HPA axis
分类号 R285.5 [医药卫生—中药学]
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参考文献16

  • 1Tyrka AR,Wier L,Price LH,et al.Childhood parental loss and adult hypothalamic-pituitary-adrenal function[J].Biol Psychiatry,2008,63(12):1 147-1 154.
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二级参考文献9

  • 1Stephen JC. Can one forget to remember? Science,2003,301 : 465.
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  • 3Bessel A,Van der Kolk. The psychobiology and psychopharmacology of PTSD. Human Psychopharmacology, 2001 , 16 : 49-64.
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  • 8Thomas S, Laxmi TR, Oliver S, et al. Amygdalar and hippocampal theta rhythm synchronization during fear memory retrieval. Science,2003,301 : 846-850.
  • 9James LM. Memory-a century of consolidation. Science,2000,287: 248-251.

共引文献38

同被引文献13

引证文献1

二级引证文献17

神经疾病与精神卫生
2010年 第4期

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