血清维生素C、E水平与2型糖尿病及其微血管并发症的关系

Association of serum vitamin C,vitamin E with micro-vascular complication in type 2 diabetes

目的:探讨2型糖尿病患者血清维生素C、E水平变化及其与微血管并发症之间的关系。方法:采用化学比色法检测60例2型糖尿病患者(糖尿病组)和20例健康人(对照组)的血清维生素C、E水平。结果:2型糖尿病组血清维生素C、E水平低于对照组(P<0.01),糖尿病伴有微血管并发症组低于糖尿病无并发症组(P<0.01)。结论:血清维生素C、E可能参与了糖尿病的发生与发展,并与糖尿病微血管并发症的发生与发展有密切的联系。

Objective： To explore the changes in serum level of vitamin C and vitamin E and the relationship between them and micro-vascular complications in patients with type 2 diabetes mellitus（T2DM）.Methods： The concentrations of vitamin C and vitamin E were measured in 60 patients with T2DM and 25 controls by chemicolorimetric methods.Results： The concentrations of vitamin C and vitamin E were higher in T2DM patients than those in controls,the concentrations of vitamin C and vitamin E in T2DM with micro-vascularcomplication were higher than those in T2DM without micro-vascular complications.Conclusion： The interaction of vitamin C and vitamin E may participate in the occurrence and development of T2DM,and correlate to the occurrence and development of diabetic micro-vascular complications.