宫颈环形电切除术在治疗宫颈上皮内瘤样变中的诊治价值

The value of LEEP in diagnosis and treatment of cervical intraepithelial neoplasia

目的:探讨宫颈环形电切除术(LEEP术)在宫颈上皮内瘤样病变(CIN)中的诊治价值。方法:分析106例经阴道镜宫颈活检诊断为CIN的患者行LEEP宫颈锥切手术治疗,观察手术时间和出血量、比较术前与术后病理检查结果,术后切缘累及,并发症及宫颈修复情况。结果:LEEP治疗CIN平均手术时间3～l6min,术中出血量5-20ml,阴道镜下宫颈活检的CIN与LEEP术后标本的病理诊断CIN符合率74.53%,术后级别上升5.66%,下降19.81%;术后切缘累及共5例,占总病例数的4.72%;术后并发症发生率为3.8%;宫颈修复率为90.57%。结论:LEEP术是诊断和治疗宫颈上皮内瘤变安全、有效的方法。

Objective：To study the effectiveness of Loop electrosurgical excision procedure （LEEP） in the diagnosis and management of cervical intraepithelial neoplasia.Methods：One hundred and six cases with cervical intraepithelial neoplasia diagnosed by biopsy were treated by LEEP.Observe the operative time and bleeding volume,cervical biopsy results before and after LEEP were evaluated,margin specimens,complications and the effects and cervical regeneration were followed up.Results：The mean operative time of LEEP was 3-16 minutes.The mean bleeding volume was 5-20ml.Pathological diagnosis of CIN after LEEP accuracy74.53% by colposcopy.The pathological grade went up 5.66%,while grade went down 19.81%.Margin specimens were involved in 5 cases （4.72%）.Incidence rate of postoperative syndrome is 3.8%;The cervical rehabilitation rate is 90.57%.Conclusion：LEEP is one of the effective and safe methods for the diagnosis and treatment of CIN.