成都市在美沙酮维持治疗门诊开展综合干预对治疗效果影响的分析

The effect of comprehensive intervention for patients receiving methadone maintenance treatment(MMT) in Chengdu

目的了解成都市综合干预对美沙酮维持治疗(MMT)效果的影响。方法采用整群抽样的方法,分别抽取2008年MMT的病人802人,2009年经过综合干预的病人806人。运用SAS 8.2对资料进行统计分析。结果干预前后,2009年与2008年MMT的病人比较,服药剂量维持大于或等于60mg/d的比例,由49.0%增高至54.7%,治疗维持率由54.5%增高至61.2%,偷吸率由34.8%降低至23.6%,偷吸≥10次的比例由44.4%降低至29.5%,社区其他人对病人治疗持支持态度的比例由66.3%增加至72.7%。结论综合干预措施有利于美沙酮维持治疗的开展,能减少脱失和提高维持治疗效果。

Objective To learn about the impact of the comprehensive intervention on MMT in Chengdu.Methods A cluster of 802 MMT patients were sampled in 2008,while 806 MMT patients were subject to comprehensive intervention in 2009.SAS 8.2 was used for statistical analysis.Results The conditions of MMT patients in 2008 and 2009 were compared.The proportion of the patients who took daily dosage of no less than 60mg/d increased from 49.0% in 2008 to 54.7% in 2009,the retention rate increased from 54.5% to 61.2%;the side using rate decreased from 34.8% to 23.6%,and the rate of side using more than 10 times also decreased from 44.4% to 29.5%,while the community＇s supportive attitude to MMT patients increased from 66.3% to 72.7%.Conclusion The comprehensive intervention is of benefit to the development of MMT programs and may help to cut down the drop out rate and improve the efficacy of MMT.