摘要
目的:为中药难溶性药物注射给药配方提供参考。方法:根据对中药难溶性成分的特点及中药注射剂的剂型特点的分析,结合各类增溶技术的特点和规律,制定其配方策略。结果:对各类配方手段进行了系统总结,并给出了简要配方策略。结论:需加快研究符合中药及中药注射剂特点的难溶性药物配方体系。
This work explored the formulation strategy for the injectable administration of insoluble TCM. A formulation strategy was presented based on the characteristics of poorly water-soluble TCM drugs and injections, the characteristic and rule of various solubilizition techniques, as well as a systematic summary of various formulation methods. It was also proposed to strengthened the study on the formulation system of poorly water-soluble drugs, which is consistent with the features of TCM and its injectable preparations.
出处
《世界科学技术-中医药现代化》
2010年第5期793-797,共5页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家中医药管理局中医药行业科研专项(200708006):符合中药特点的增溶性药用辅料的筛选与评价,负责人:杨明,子课题负责人:乔延江
关键词
难溶性药物
增溶
注射给药
中药注射剂
配方策略
Poorly Water-soluble Drug, Solubilization, Injection administration, T.C.M. Injections, Formulation Strategy