树突状细胞和自然杀伤细胞与肿瘤细胞端粒酶的研究进展
Dendritic cells and natural killer cells in relation to tumor cell telomerase： research advances
摘要
树突状细胞（DC）将人端粒酶逆转录酶（hTERT）提呈给T淋巴细胞，可激发特异性的细胞毒性T细胞和CD4＋T细胞反应。自然杀伤（NK）细胞与肿瘤细胞端粒酶的相关研究较少，而DC和NK细胞共同作用可以增加抗肿瘤活性，有可能与端粒酶共同参与抗肿瘤免疫反应。
Dendritic cells （DC） present telomerase reverse transcriptase（hTERT） to T lymphocytes, stimulating specific reactions of cytotoxic T cells and CD4 ＋ T cells. Researches on the relationship between nat- ural killer （NK） cells and telomerase of tumor cells are scarce. DC and NK cells act together promoting anti- tumor responses and possibly participate in anti-tumor immune responses with telomerase.
出处
《国际肿瘤学杂志》
CAS
2010年第10期726-728,共3页
Journal of International Oncology
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