亚麻醉剂量丙泊酚对术后恶心呕吐的作用研究

The effect of subanesthetic dosage propofol on postoprative nausea and vomitting

目的:观察丙泊酚对术后恶心呕吐的的影响。方法:选择ASAI-II级蛛网膜下腔和硬膜外联合穿刺麻醉下行妇科全子宫切除手术患者80例,随机分为4组,每组20例。C组为空白对照组,P组为安慰剂对照组,A组为恩丹西酮组,B组为丙泊酚组。结果:A组和B组的恶心和呕吐的发生率明显的低于C组(P<0.05)。P组和C组恶心呕吐的发生率无显著性差异。A组和B组术后恶心呕吐的发生率无显著性差异。结论:丙泊酚可降低椎管内麻醉患者术后恶心呕吐的发生率。

Objective： To investigate the effect of Propofol on postoprative nausea and vomitting. Methods： Eighty ASA I-II female patients were randomly assigned to foue groups （n=20 each）： control group（C）, placeboo group （P）, ondansetron group（A）, propofol group （B）. Results： The incidence of PONV in the A and B groups were significantly lower than in the C group（P〈0.05）. The incidences of PONV were not different between the A and B groups. Conclusion： Propofol can greatly reduce the incidence of PONV.