HBV感染免疫状态与HBV基因型关系研究思路

Relationship between immune status of HBV infection and HBV genotype

HBV感染免疫状态不同,临床意义不同;HBV基因型不同,导致病毒致病性、变异、抗病毒等临床疗效及预后不同。HBV感染临床意义的不同,是宿主与病毒共同作用的结果。将HBV感染免疫状态与HBV基因型结合在一起研究,探索广西桂北地区不同免疫状态下基因型的分布情况及HBV感染免疫状态与基因型的关系,并希期望能针对宿主免疫状态、病毒特性,为每一位HBV感染患者制订最好的治疗方案。

The immune states of Hepatitis B Virus（HBV） infection are different,and the clinical significance of HBV infection is different. On the same time, because the genotypes of HBV are various. There are the difference of the virus pathogenicity, variation, antivirus treatment and prognosis. They are the result of host and virus. The research of immune states of HBV infection and genotypes of HBV should investigate the distribution of genotypes of HBV in the north of Guangxi and the relation between of them.So than making the best therapeutic schedule to every patient of HBV infection by aimming at the immune states of host and characteristics virus, such as the genotypes of HBV.