薄荷脑与β-环糊精的包合作用

Study on the Inclusion Effect of Menthol with β-Cyclodextrin

用三种制备方法考察了β-CD对薄荷脑的包合作用,经物理常数测定和含量分析证实β-CD与薄荷脑确实已形成包合物,而且有1:1型和2:3型两种组成。差热分析结果显示,该包合物的气化温度远高于纯薄荷脑的气化温度,只有将其解络后,才能与纯薄荷脑同条件下进行气相测定。

Indusion effect of βBB-CD with menthol was studied by three methods of preparation. Determination of physical constants and quantitative analysis proved that the inclusion compounds of β-CD with menthol were formed, which was found to be 1 :1 and 2:3.The results of thermal analysis demmonstrated that the gasifiadon temperature of the inclusion compounds was by far higher than that of the free menthol.It was considered that the inclusion compound must be disconnected to be free, and then it can be determined by gas chromatography in the same condition of the free menthol.