甲状腺功能亢进性心脏病的Q-T离散度分析

Analysis of Q - T dispersion in patients with hyperthyroidism heart disease

为探讨甲状腺功能亢进性心脏病的Q-T离散度(Q-T_d及Q-T_(cd))变化的意义,分析41例甲状腺功能亢进性心脏病患者的体表12导联心电图并与42例单纯甲状腺功能亢进症患者及42例正常人作对照.结果显示甲状腺功能亢进性心脏病组Q-T_d、Q-T_(cd)均显著高于其余两组(P<0.01).以Q-T_d>42ms判为异常,诊断甲状腺功能亢进性心脏病的敏感性、特异性及准确性分别为82.9%、86.9%及85.6%;以Q-T_(cd)>46ms判为异常,诊断敏感性、特异性及准确性分别为82.9%、89.3%及87.2%.提示甲状腺功能亢进性心脏病患者的Q-T_d、Q-T_(cd)延长可作为临床诊断的一项参考指标.

In order to investigate clinical significance of change of Q - T dispersion(Q-Td and Q - Tcd) in patients with hyperthyroidism heart disease, Q - T dispersion (Q - Td and Q - Tcd) of 12 - lead surface ECG was measured in 41 cases with hyperthroid heart disease, 42 cases with hyperthyroidism and 42 cases of healthy adults for control .Results showed that Q-Td and Q - Tcd in patients with hyperthyroidism heart disease increased markedly than that with hyperthyroidism and healthy adults(P < 0.01) . Q - Td higher than 42 ms had a sensitivity of 82.9% , specificity of 86.9% , accuracy of 85.6% for diagnosis of hyperthyroidism heart disease. Q - Tcd higher than 46 ms had a sensitivity of 82.9% , specificity of 89.3% , accuracy of 87.2% for diagnosis of hyperthyroidism heart disease.It indicated that Q-Td and Q-Tcd in patients with hyperthyroidism heart disease increased, result suggested that myocardial repolarization was not in association. It indicated that Q - Td and Q - Tcd may provide new information for diagnosis in hyperthyroidism heart disease.