3Clasus N, Tobias H, Stefan L, et al. Long- term follow- up HBeAgpositive patients treated with interferon alfa for chronic hepatitis B[J]. N Engl J Med, 1996,334:1422- 1427
4Ching LL, Rong NC, Leung N, et al. A one - year trial of lamivudine for chronic hepatitis B[J]. N Engl J Med, 1998,339:61 -68.
5Pol S, Michel ML, Brechot C. Immune therapy of hepatitis B virus chronic infection[J]. Hepatology,2000,31:548 - 549.
6Couillin I, Pol S, Mancini M, et al. Specific vaccine therapy in chronic hepatitis B: Induction of T cell proliferative responses specific for envelope antigens[J]. J Infect Dis, 1999,180:15 - 26.
7Pol S, Nalpas B, Driss F, et al. Efficacy and limitations of a specific immunotherapy in chronic hepatitis B[ J]. Hepatol, 2001,34:917- 921.
8Akbar SMF, Abe M, Matsumoto T, et al. Mechanism of action of vaccine therapy in murine hepatitis B virus carriers:vaccine- induced activation of antigen presenting dendritic cells[ J]. J Hepatol, 1999,30: 755 - 764.
9Franco A, Guidotti G, Hobbs MV, et al. Pathogenetic effector function of CD4^+ - postive T helper 1 cells in hepatitis B virus transgenic mice[J].J Immunol, 1997,159:2001 - 2008.
