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乳腺癌骨转移机制的研究进展 被引量：5

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摘要 前言乳腺癌是女性最常见的恶性肿瘤之一,死亡率仅次于肺癌,居第二位。乳腺癌也是最常见的转移性肿瘤之一,乳腺癌术后的远处转移以骨、肺、肝多见;有数据表明,骨骼是其最常见的转移部位。肿瘤转移是一个复杂的多步骤的过程,任何转移部位都有典型环境障碍.
作者 何战洋 应学翔 何萍青
机构地区 上海交通大学附属第六人民医院普外科
出处 《外科理论与实践》 2010年第5期550-553,共4页 Journal of Surgery Concepts & Practice
关键词 乳腺癌 肿瘤骨转移 病理机制
分类号 R737.9 [医药卫生—肿瘤] R73-37 [医药卫生—肿瘤]
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参考文献32

  • 1Mundy GR.Metastasis to bone:causes,consequences and therapeutic opportunities[J].Nat Bey Cancer,2002,2(8):584-593.
  • 2Chen C.An approach to the relevance between varations in hormone secretion and the incidence of hyperplasia of mammary glands and mammary cancer[R].2004,ISPO Meeting.
  • 3Suva LJ,Griffin RJ,Makhoul I.Mechanisms of bone metastases of breast cancer[J].Endocr Relat Cancer,2009,16(3):703-713.
  • 4Pratap J,Javed A,Languino LR,et al.The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion[J].Mol Cell Biol,2005,25(19):8581-8591.
  • 5Tomita A,Kasaoka T,Inui T,et al.Human breast adenocarcinoma(MDA-231)and human lung squamous cell carcinoma(Hara)do not have the ability to cause bone reserption by themselves during the establishment of bone metastasis[J].Clin Exp Metastasis,2008,25(4):437-444.
  • 6Veldkamp CT,Seibert C,Peterson FC,et al.Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12[J].Sci Sigual,2008,1(37):29-34.
  • 7Kaplan RN,Riba RD,Zacharoulis S,et al.VEGFR1positive haematopoietic bone marrow progenitors initiate the pre-Metastatic niche[J].Nature,2005,438(7069):820-827.
  • 8Shimo T,Nakanishi T,Nishida T,et al.Involvement of CTGF,a hypertrophic chondrocyte-specific gene product,in tumor angiogenesis[J].Ontology,2001,61(4):315-322.
  • 9Bellahcène A,Bonjean K,Fohr B,et al.Bone sialoprotein mediates human endothelial cell attachment and migration and promotes angiogenesis[J].Circ Res,2000,86(8):885-891.
  • 10Waltreguy D,Bellahcène A,de Leval X,et al.Increased expression of bone sialoprotein in bone metastases compared with visceral metastases in human breast and prostate cancers[J].J Bone Miner Res,2000,15(5):834-843.

同被引文献67

  • 1傅正,卢奕,姚智.OPG RANKL和RANK在肿瘤骨转移中的作用[J].中国肿瘤临床,2004,31(22):1316-1318. 被引量：7
  • 2王涛,宋三泰,江泽飞,卞寿庚,王雅杰,李丽庆,朱军.伊班膦酸治疗恶性肿瘤性高钙血症的临床研究[J].中华肿瘤杂志,2004,26(12):739-741. 被引量：25
  • 3庞丹梅,林爱珍,邓燕明.动态检测乳腺癌患者血清TPS和CA153的临床意义[J].实用肿瘤学杂志,2006,20(3):226-227. 被引量：7
  • 4Guise TA,Brufsky A,Coleman RE.Understanding and optimizingbone health in breast cancer[J].Curr Med Res Opin,2010,26(Suppl 3):3-20.
  • 5Diel IJ.Bisphosphonates in breast cancer patients with bone metas-tases[J].Breast Care(Basel),2010,5(5):306-311.
  • 6Fili S,Karalaki M,Schaller B.Mechanism of bone metastasis:therole of osteoprotegerin and of the host-tissue microenvironment-re-lated survival factors[J].Cancer Lett,2009,283(1):10-19.
  • 7Chappard D,Bouvard B,BasléMF,et al.Bone metastasis:histolog-ical changes and pathophysiological mechanisms in osteolytic or os-teosclerotic localizations.A review[J].Morphologie,2011,309(95):65-75.
  • 8Rosen LS,Gordon DH,Dugan WJ,et al.Zoledronic acid is superiorto pamidronate for the treatment of bone metastases in breast carci-noma patients with at least one osteolytic lesion[J].Cancer,2004,100(1):36-43.
  • 9Coleman RE,Major P,Lipton A,et al.Predictive value of bone re-sorption and formation markers in cancer patients with bone metas-tases receiving the bisphosphonate zoledronic acid[J].J Clin On-col,2005,23(22):4925-4935.
  • 10Zheng Y,Zhou H,Fong-Yee C,et al.Bone resorption increasestumour growth in a mouse model of osteosclerotic breast cancer me-tastasis[J].Clin Exp Metastasis,2008,25(5):559-567.

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外科理论与实践
2010年 第5期

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