复方氨基酸注射液20AA在晚期肝包虫术后应用的疗效

Compound amino acid injection 20AA in hepatic echinococcosis after surgery

目的观察晚期肝包虫患者术后应用复方氨基酸注射液20AA的疗效。方法选择行肝包虫手术后成年患者60例,分为2组:对照组(n=30)应用18种氨基酸注射液,研究组(n=30)应用复方氨基酸注射液20AA,均500 mL,qd。采用全营养混合液方式行周围或中心静脉输注,等氮等热量。从手术当日即开始应用,共7 d,在手术前1 d及术后d 7,检测血清总蛋白和清蛋白。结果术前血清总蛋白、清蛋白浓度2组比较无显著差异(P>0.05)、术后均有降低,但与术前比较研究组无显著差异(P>0.05),对照组有显著差异(P<0.01)。2组手术后体重指数均降低,但研究组与手术前比较无显著差异(P>0.05),对照组有显著差异(P<0.05)。术后2组间比较有显著差异(P<0.01)。结论对晚期肝包虫术后患者应用复方氨基酸注射液20AA进行营养支持疗效较好。

AIM To investigate the therapeutic effects of compound amino acid injection 20AA in hepatic echinococcosis after surgery.METHODS Sixty patients with hepatic echinococcosis were randomized into control group（n = 30,administered with compound 18 injection amino acid）,（18-F） and trial group（n = 30）,received compound amino acid injection 20AA,500 mL,qd equally.From the first day after surgery,total parenteral nutuition was infused to the patients with equal nitrogen by central or peripheral vein for 7 days.Fasting blood samples were collected 1 day before surgery and 7 day after surgery.Serum total protein and albumin were measured.RESULTS There was no significant difference in serum total protein and albumin between two groups before surgery（P 0.05）.Compared with before surgery,serum total protein,albumin and body mass index（BMI） decreased in both groups after surgery,but there was no significant difference（P 0.05） in the trail group,there was significant difference（P 0.05） in the control group.There were significant difference in serum total protein,albumin and BMI between two groups after surgery（P 0.01）.CONCLUSION Compound amino acid injection 20AA is effective in patients with hepatic echinococcosis after surgery.