血中酒精浓度的回推算研究

Study on retrograde extrapolation of blood alcohol concentration

目的研究血中酒精浓度值(BAC值)的推算关系。方法对327位自愿受试者饮酒后测定其血中酒精时浓曲线进行分析,计算血中酒精清除率。结果血中酒精消除呈线性,327例血液中酒精消除线性相关系数为0.985±0.019,最小绝对值为0.98,最大绝对值1.000,消除斜率绝对值平均为(0.136±0.037)mg/mL/h,最小绝对值为0.075mg/mL/h,最大绝对值0.266mg/mL/h。结论血液中酒精浓度的推算可根据线性消除关系回推,血液中酒精浓度按照每小时下降0.10mg进行回推算。

Objective To make the study on retrograde extrapolation of blood alcohol concentration（BAC）.Methods The elimination rate of 327 subjects′BAC was calculated according to the curve of blood alcohol concentration with time.Results The elimination of BAC conform to the mode of linear elimination.The correlation coefficient obtained was 0.985±0.019.The minimium value was 0.98,and maximium value 1.00.The overall mean value of the blood alcohol elimination rate was（0.136±0.037）mg/mL/h.The minimium value was 0.075 mg/mL/h,and maximium value 0.266 mg/mL/h.Conclusion The retrograde extrapolation of BAC can be calculated according to the correlation coefficient of linear elimination.The elimination rate used for a person in back calculation was 0.10mg/mL/h.