雌激素促进药物流产后的子宫内膜修复

Estrogen promoting endometrium regeneration after medical abortion

目的：探讨在药物流产后使用雌激素对缩短阴道出血时间的作用。方法：早孕行药物流产患者，随机分为实验组和对照组各104例。实验组从胎囊排出的第5天开始每天服用补佳乐1mg14～18d。了解阴道出血时间、子宫内膜修复和宫内残留情况。结果：实验纽药流后阴道出血时间平均为10．61d，明显缩短，对照组15．7d（t=5．802，P〈0．05）。药流后2周，B超检查在实验组中55．8％（58／104）有内膜修复，而对照只有17．3％（18／104）修复，差异有显著性（x^2=7．741，P〈0．05）。结论：药流胎囊排出后加用雌激素，可促进子宫内膜修复，缩短阴道出血时间．

Obiective To observe the effect of estrogen on endometrium and vaginal bleeding duration after medical abortion. Method The104 cases with medical abortion were randomly divided into observation and control group. After embuyo was ejected, Progynva was take orally ling. d-114-18days in the observation group on fifthly, day of embryo ejected. For all cases, bleeding duration was followed up, endometrium regeneration and remaining were re-examined with B ultrasound after 2 and 3 weeks. Result Average bleeding duration were 10.61 and 15.73 days in observed and control group respectively（t=5.802, p〈 0.05）. Endometrium regeneration was found in 55.8% i58/104） cases in observed group and only 17.3%（18/54）in control（x^2=7.741, p〈 0.05）. Conclusion Estrogen added to medical abortion may promote endometrium regeneration and decrease bleeding duration.