^(99m)Tc-MIBI显像对甲状腺“冷(凉)结节”良、恶性鉴别的临床价值

Clinical value of ^(99m)Tc-MIBI imaging for differentiating benign from malignant cold thyroid nodules

目的探讨99mTc-MIBI显像对甲状腺冷(凉)结节良、恶性鉴别的临床价值。方法 75例99mTcO4-甲状腺显像为"凉(冷)结节"患者,均行99mTc-MIBI显像,其显像结果与术后病理结果相对照。结果 75例患者中,99mTc-MIBI显像呈阳性者32例,其中经病理诊断18例为恶性肿瘤,14例为良性病变;99mTc-MIBI显像呈阴性者43例,经病理诊断后40例为良性病变,3例为恶性肿瘤。本组99mTc-MIBI显像的诊断灵敏度为85.71%,特异性为74.07%,准确性为77.33%。结论 99mTc-MIBI核素显像对甲状腺结节良、恶性鉴别诊断的特异性低,单独应用受限,但可作为其他诊断方式非常重要的辅助手段。

Objective To evaluate the clinical value of 99mTc-MIBI imaging for differentiating benign from malignant cold thyroid nodules. Methods Seventy-five patients with cold thyroid nodules underwent 99mTc-MIBI scintigraphy and subsequently the imaging findings of all the patients were prospectively analyzed and compared with those of surgery and pathology. Results Among 75 cases,99mTc-MIBI imaging showed 32 positive patients who comprised 18 malignant and 14 benign lesions confirmed by pathology,while other 43 cases were negative patients who comprised 40 benign and 3 malignant lesions confirmed by pathology. The sensitivity,specificity and accuracy of 99mTc-MIBI imaging for detecting cold thyroid nodules in the group were 85.71%,74.07% and 77.33%,respectively. Conclusion Although the specificity of 99mTc-MIBI scintigraphy in differentiating benign from malignant cold thyroid nodules is lower and its alone use is limited but it can be taken as an important complement to other diagnostic modalities.