Tau蛋白异常修饰及其相关调控机制的研究进展
出处
《中国老年学杂志》
CAS
CSCD
北大核心
2010年第20期3029-3032,共4页
Chinese Journal of Gerontology
基金
国家自然科学基金(3086085)
云南省应用基础研究项目(2007C177M)
云南省中青年学术技术带头人后备人才基金资助项目(2006YP01-07)
参考文献37
-
1Cleveland DW,Hwo SY,Kirschner MW.Purification of tau,a microtubule-associated protein that induces assembly of microtubules from purified tubulin[J].J Mol Biol,1977;116(2):207-25.
-
2Boyne LJ,Tessler A,Murray M,et al.Distribution of Big tau in the central nervous system of the adult and developing rat[J].J Comp Neurol,1995;358(2):279-93.
-
3Komori T.Tau-positive glial inclusions in progressive supranuclear palsy,corticobasal degeneration and Pick′s disease[J].Brain Pathol,1999;9(4):663-79.
-
4Reynolds CH,Garwood CJ,Wray S,et al.Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase,phospholipase Cgamma1,Grb2,and Src family kinases[J].J Biol Chem,2008;283(26):18177-86.
-
5Lebouvier T,Scales TM,Williamson R,et al.The microtubule-associated protein tau is also phosphorylated on tyrosine[J].J Alzheimers Dis,2009;18(1):1-9.
-
6Michel G,Mercken M,Murayama M,et al.Characterization of tau phosphorylation in glycogen synthase kinase-3beta and cyclin dependent kinase-5 activator(p23)transfected cells[J].Biochim Biophys Acta,1998;1380(2):177-82.
-
7Sun Q,Gamblin TC.Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization[J].Biochemistry,2009;48(25):6002-11.
-
8Giese KP.GSK-3:a key player in neurodegeneration and memory[J].IUBMB Life,2009;61(5):516-21.
-
9Shimura H,Schwartz D,Gygi SP,et al.CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival[J].J Biol Chem,2004;279(6):4869-76.
-
10Cruz JC,Tseng HC,Goldman JA,et al.Aberrant CDK5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles[J].Neuron,2003;40(3):471-83.
-
1张真真,苏帆,纪木火,杨建军.术后认知功能障碍生物标记物的研究进展[J].临床麻醉学杂志,2016,32(6):616-620. 被引量:18
-
2王琦,王文安.Aβ蛋白和tau蛋白与阿尔茨海默病的相关性研究进展[J].医学综述,2013,19(11):1921-1923. 被引量:4
-
3王建枝,龚成新,I.GRUNDKE-IQBAL,K.IQBAL.阿尔次海默病tau蛋白异常修饰与其功能的关系[J].生物化学与生物物理进展,1999,26(2):154-157. 被引量:1
-
4胡轶虹,白春艳,周艳,孙宏侠.阿尔茨海默病的生物标志物研究进展[J].中风与神经疾病杂志,2016,33(1):90-92. 被引量:3
-
5儿童自闭症与基因变异有关[J].大众健康,2009(7):6-6.
-
6Fost.,NL,万新华.连锁于17号染色体,伴帕金森病的额颞叶痴呆:医师指南[J].世界医学杂志,2000,4(7):13-19.
-
7苗青,闫福岭,张干,王菲,吴松,董利,叶斌.维生素E对Alzheimer病模型大鼠海马过磷酸化tau蛋白含量的影响[J].蚌埠医学院学报,2008,33(3):276-278.
-
8李国栋,袁保梅,鄢文海,邢莹.人参皂苷Rb1对内源性Aβ所致小鼠神经细胞Tau蛋白过磷酸化的干预作用[J].山东医药,2009,49(3):26-28. 被引量:3
-
9刘冲.Tau病(Tauopathy)[J].日本医学介绍,2005,26(12):576-576.
-
10SoniaM.Rosso,王伊龙.与17号染色体有关的前额颞疾病及帕金森综合征最新研究进展[J].世界医学杂志,2002,6(24):6-8.