1Vernon MW, Wilson EA. Studies on the surgical induction of endometriosis in the rat[ J ]. Fertil Steril, 1985,44:684- 694.
2Aytan H, Caglar P, Uygur D, et al. Effect of the immunomodulator leflunomide on the induction of endometriosis in an experimental rat model [ J ]. Fertil Steril,2007,87 : 699- 702.
4Harada T, lwabe T, Terakawa N, et al. Role of cytokines in endometriosis[ J]. Fertil Steril,2001,76 : 1-10.
5Jolicueur C, Boutouil M, Drouin R, et al. Increased expression of monocyte chemoatlractant protein-1 in the endometrium of women with endometriosis [ J ]. Am J Pathol, 1998,152 : 125-133.
6Kayisli UA, Mahutte NG, Arici A. Uterine chemokines in reproductive physiology and pathology [ J ]. Am J Reprod Immunol, 2002,47 : 213-221.
7Rossi M, Sharkey AM, Vigano P, et al. Identification of genes regulated by interleukin-1 beta in human endometrial stromal cells [ J ]. Reproduction, 2005,130 : 721-729.
8Bergqvist A, Bruse C, Carlberg M, et al. Interleukin-lbeta,interleukin-6 and tumor necrosis factor-alpha in endometriotic tissue and in endometrium [ J ]. Fertil Steril, 2001,75:489-495.
9Klimiuk PA, Kita J, Chwiecko J,et al. The changes in serum chemokines following leflunomide therapy in patients with rheumatoid arthritis [ J ]. Clin Rheumatol, 2009,28 : 17-21.
10Elkayam O, Yaron I, Shirazi I, et al. Active leflunomide metabolite inhibits interleukin 1 β, tumour necrosis factor a, nitric oxide, and metalloproteinase-3 production in activated human synovial tissue culture [ J ]. Ann Rheum Dis, 2003,62 : 440-443.
6Aytan H, Caglar P, Uygur D, et al. Effect of the immunomodulator leflunomide on the induction of endometriosis in an experimental rat [ J ]. model Fertil Steril,2007,87 (3) :698-701.
7Sakamoto Y, Harada T, Horie S, et al. Tumor necrosis factor- al- pha - induced interleukin - 8 ( IL - 8) expression in endometriot- ic stromal cells, probably through nuclear factor - kappa B activa- tion : gonadotrepin - releasing hormone agonist treatment reduced IL - 8 expression [ J ]. J Clin Endocrinol Metab, 2003,88 ( 2 ) : 730-5.
9Xu X,Williams JW,Gong H,et al. Two activities of the immuno- suppressive metabolite of leflunomide, A77 1726. Inhibition of py rimidine nucleotide synthesis and protein tyrosine phosphorylation [J]. Biochem Pharmacol, 1996,52(4) = 527-534.
10Latchoumycandane C, Seah QM, Tan RC, et al. Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK mediated mitoehondrial permeability transition in immortalized human hepatocytes[J]. Toxicol Appl Pharmacol, 2006,217(1):125 133.
