基于星形胶质细胞靶点的抑郁症发病机制研究进展

Research advancement of depression pathogenesis on astrocyte targets

抑郁症是具有自杀倾向的情感性精神障碍,其机制尚未完全阐明。随着对其研究的不断深入,一些非单胺类神经递质假说机制被陆续发现,特别是星形胶质细胞功能障碍在其中起重要作用。该文就星形胶质细胞靶点的抑郁症发病机制进行综述。

Depression is a kind of affective disorders that may lead to suicide;its pathogenesis is not clear.With the further study,some non-monoamine-based mechanisms have been found,especially in the field of astrocyte disturbance,which plays a key role in the progress of morbility.This article is a review of the advancement in the study of the pathogenesis of depression on astrocyte targets.