实时全容积三维超声心动图初步评价正常胎儿心室容积和心室收缩功能

Assessment of fetal ventricular volume and systolic function using real-time three-dimensional echocardiography

目的 探讨实时三维超声在研究正常胎儿心室发育和心室收缩功能方面的价值.方法 回顾分析54例正常胎儿全容积三维数据,通过后处理软件获得心室容积参数,包括舒张末期容积（EDV）、收缩末期容积（ESV）和搏出量（SV）及心室收缩功能参数射血分数（EF）,分析胎儿心室容积发育与孕周的关系,比较左右心室容积和收缩功能的差异.结果 胎儿左右心室容积参数EDV、ESV、SV与孕周间均有线性相关关系,随孕周增长而增加,而收缩功能参数EF与孕周之间无明显线性关系,随孕周增长无明显变化 容积参数EDV、ESV左右心室之间差异无明显统计学意义,而SV、EF左右心室间差异有统计学意义（P＜0.05）.结论 实时三维超声对胎儿心内膜清晰成像时能够获得心室腔容积,进而评价心脏收缩功能,有助于进一步研究胎儿心脏容积发育和收缩功能变化.

Objective To discuss the worthiness of real-time three-dimensional echocardiography in researching normal fetal heart ventricle growth and systolic function. Methods End-systolic volume（EDV）,end-diastolic volume（ESV）, struggle volume（SV） and ejection fraction（EF） of 54 normal fetal were acquired from 3-D data by Qlab software. The relation between ventricular growth with pregnant week was analysed and the difference of the volume and systolic function between left ventricle with right ventricle were compared. Results Ventricular volume of normal fetal heart （EDV,ESV,SV） were all increased with the gestational ages,there was linear relativity between them,while EF was not increased with pregnant weeks,there was no linear relativity between them. There was no statistics difference on EDV and ESV between left ventricle and right ventricle, while there was statistics difference on SV, EF between them. Conclusions The image of fetal endocarium could be derived clearly by real-time three-dimensional echocardiography, which help to get fetal heart ventricular volume and to study fetal heart growth and function.