超声双重造影在胃间质瘤诊断中的价值

Clinical value of double contrast-enhanced ultrasonography in the diagnosis of gastric stromal tumors

目的 评价超声双重造影（DCUS）对胃间质瘤（GST）的诊断价值.方法 对26例胃间质瘤的DCUS表现与病理诊断结果进行对照分析.结果 26例胃间质瘤中病理诊断为低危16例,高危10例.口服胃窗超声造影检查定位诊断正确率76.9%（20/26）,DCUS定位诊断正确率为100%（26/26）,两者比较差异有统计学意义（P=0.023）.胃间质瘤的生物学行为与病灶大小、形态、内部有无坏死、液化及超声造影增强模式有关（P＜0.05）,与病灶的边界及有无转移无关（P＞0.05）.26例患者中,口服胃窗超声造影检出病灶中坏死液化区7例,DCUS检出病灶中坏死液化区13例,两者比较差异有统计学意义（x2=4.426,P=0.035）.结论 DCUS可用于胃间质瘤的定性和定位诊断,可为胃间质瘤的治疗方案选择提供指导和参考意见.

Objective To evaluate clinical value of double contrast-enhanced ultrasonography（DCUS）in diagnosing gastric stromal tumors（GST）. Methods The medical records of 26 patients with a histological diagnosis of GST were retrospectively reviewed. The correlation between DCUS features and pathological findings of the lesions was compared. Results Total 26 cases of GST were divided into low risk group（ 16 cases） and high risk group （10 cases）. The size,contour,liquefactive necrosis and enhancement distribution of lesions were markedly correlated with the pathobiologic behaviour of the tumor （ P 〈0.05）. There was no significant difference in border and metastasis of lesions between two groups（ P 〉0.05）. It was shown that DCUS supplied statistically significant improvement in the localization diagnosis and detection of liquefactive necrosis versus oral contrast-enhanced ultrasonography （ P 〈 0.05 ）. Conclusions DCUS is considered as a valuable tool in diagnosing location as well as pathobiological behaviour of GST. It can provide the guidance and reference comments for treatment algorithms.