超声造影在典型及非典型乳腺癌诊断中的价值

Diagnostic value of contrast-enhanced ultrasonography in typical and atypical breast cancer

目的 探讨实时超声造影技术在典型乳腺癌及非典型乳腺癌诊断中的应用价值.方法 回顾性分析73例经二维超声检查后分类的51例典型乳腺癌及22例非典型乳腺癌的实时超声造影结果,比较二者在灌注特点和灌注方式中的差异.结果 本研究73例乳腺癌中51例典型乳腺癌和22例非典型乳腺癌在灌注期血管形态、达峰期增强形态、达峰期增强水平、灌注方式之间的差异无统计学意义（P＞0.05）,二者均以树枝状或环状不均匀高增强为主,占92%（67/73）,灌注方式有快进慢退、快进-延迟-慢退、同进同退三种,分别占48%（35/73）,44%（32/73）,8%（6/73）.结论 非典型乳腺癌与典型乳腺癌的造影模式相似,二者的造影模式均以快进慢退、快进-延迟-慢退和环状或树枝状高增强为主,应用超声造影可显著提高乳腺恶性病变、尤其是非典型乳腺癌的诊断准确率.

Objective To investigate the diagnostic value of contrast enhanced ultrasound in breast cancer. Methods Thirty-six cases including 51 typical and 22 atypical breast cancer were examined with injecting contrast agent before operation. The enhanced charaters of perfusion pattern, enhanced level, and modes were observed and reanalyzed when pathology was got. Results There was no statistical meanings in perfusion pattern, enhanced level and mode between typical and atypical breast cancer. They all enhanced like branch or annulus with high lever and there were 3 enhanced modes：＂fast in slow out＂（48% ,35/73） ,＂lastly fast in slow out＂（44% ,32/73） and ＂same in same out＂（8% ,6/73）. Conclusions The enhanced modes of breast cancer showed ＂fast in slow out＂ , ＂lastly fast in slow out＂and ＂same in same out＂, enhanced like ＂branch or annulus＂ and high level enhanced. Contrast enhanced ultrasound can increase the diagnostic accuracy in the early stage of breast cancer.