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p16、PCNA联合检测对恶性浆膜腔积液的诊断价值

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摘要 目的:探讨p16、PCNA联合检测在恶性浆膜腔积液鉴别诊断中的价值。方法:采用免疫细胞化学法,分别对22例结核性浆膜腔积液和41例恶性浆膜腔积液进p16、PCNA检测。结果:p16在结核性浆膜腔积液组和恶性浆膜腔积液组中阳性率分别为72.73%、17.07%,PCNA在结核性浆膜腔积液组和恶性浆膜腔积液组中阳性率分别为45.45%、87.80%,统计学分析,p〈0.05。结论:p16在结核性浆膜腔积液中的表达优于恶性浆膜腔积液;PCNA在恶性浆膜腔积液中的表达优于结核性浆膜腔积液。联合检测p16、PCNA可提高浆膜腔积液鉴别诊断的灵敏度,具有一定的临床参考价值。
出处 《中国中医药咨讯》 2010年第31期112-113,共2页
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