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维生素E抑制3T3-L1前脂肪细胞的分化 被引量：4

Inhibitory effect of vitamin E on differentiation of 3T3-L1 preadipocyte
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摘要 目的:研究维生素E对3T3-L1前脂肪细胞增殖和分化的影响。方法:利用MTT研究维生素E对3T3-L1前脂肪细胞增殖的影响,利用油红O染色法测定维生素E对3T3-L1前脂肪细胞分化的影响。结果:维生素E对3T3-L1前脂肪细胞增殖无影响,10～100μmol/L维生素E能抑制3T3-L1前脂肪细胞的分化。结论:维生素E对前脂肪细胞分化具有抑制作用。 Objective：To study the effects of vitamin E on proliferation and differentiation of 3T3-L1 preadipocyte.Methods：The effect of vitamin E on the proliferation of 3T3-L1 was determined by MTT.Oil red O staining was used to determine the differentiation rate and level of 3T3-L1 preadipocytes.Results：Vitamin E inhibited the differentiation of preadipocytes at 10 μmol/L and 100 μmol/L.Conclusions：Vitamin E could inhibit the differentiation of 3T3-L1 preadipocyte.
作者 郑奕迎 刘声远 马兰 龙儒桃
机构地区 海南医学院病理生理学教研室 华中科技大学同济医学院病理生理学系
出处 《海南医学院学报》 CAS 2010年第9期1117-1119,共3页 Journal of Hainan Medical University
基金 海南省自然科学基金资助项目(808164)~~
关键词 维生素E 碘 3T3-L1 增殖 分化 肥胖 MTT 油红O染色法 Vitamin E； Iodine； 3T3-L1； Proliferation； Differentiation； Obesity； MTT； Oil red staining；
分类号 Q581 [生物学—生物化学] Q254 [生物学—细胞生物学]
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参考文献8

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  • 2郑奕迎,刘声远,刘笑然,贝宁,龙儒桃.硒对3T3-L1前脂肪细胞增殖和分化的影响[J].海南医学院学报,2008,14(5):489-490. 被引量：1
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二级参考文献11

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海南医学院学报
2010年 第9期

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