肌钙蛋白和心室晚电位联合检测在小儿病毒性心肌炎监测中的意义

The significance of troponin and ventricular late potentials in detecting pediatric viral myocarditis

目的 研究肌钙蛋白（cTnI）及心室晚电位（VLP）在儿童病毒性心肌炎（VM）的临床价值.方法 102例病毒性心肌炎患儿分为轻、重两组,同时检测肌钙蛋白及心室晚电位,通过对轻、重两组的统计分析,观察CTNI及VLP在VM的快速诊断及病情严重程度中的意义,选择同期健康检查儿童作健康对照组.结果 轻症及对照组心室晚电位均为阴性,重症组心室晚电位阳性率为75%;肌钙蛋白在心肌炎组阳性率为94.5%,对照组均为阴性.轻症VM组与重症VM组对比,差异有显著性.结论 心室晚电位和肌钙蛋白联合检测能对病毒性心肌炎患儿的诊断及病情严重程度及预后做出判断.

Objective To explore the clinical value of troponin and ventricular late potentials in detecting pediatric viral myocarditis. Methods Troponin and ventricular late potentials were detected in 102 children with viral myocarditis who were divided into mild group （ 78 chilcren ） and severe group （ 24 children ）. Health children were used as control.Results Ventricular late potentials were negative in the mild group and control group, but positive in 75% of severe pediatric patients.Troponin was positive in 94.5% of the pediatric patients, but negative in the control group （ P〈0.05 ）.Conclusions Detection of both troponin and ventricular late potentials can help to diagnose pediatric viral myocarditis and judge the severity and prognosis of the disease.