梅毒阳性宫颈癌患者临床及预后分析

A clinical and prognostic analysis of 32 patients with cervical cancer complicated with syphilis

目的 探讨梅毒阳性宫颈癌患者的临床病理特点及影响预后的因素.方法 回顾性分析1990年1月至2010年7月在我院进行治疗的32例梅毒阳性宫颈癌患者的临床病理资料.应用Kaplan-Meier法进行生存分析,Logistic回归进行多因素分析.结果 32例患者的中位生存时间为22个月（95%CI：16.46～27.54）.患者的3年生存率为31.3%,5年生存率为9.4%.临床分期是无瘤生存期的独立危险因素.结论 梅毒阳性宫颈癌患者预后较差,对这些患者要做到早期发现并进行规范化的综合治疗.

Objective To explore the clinicopathological features and prognostic factors of patients with cervical cancer complicated with syphilis.Methods The clinical data on 32 ptients who had been hospitallized from January 1990 to July 2010 were retropesctively analyzed.Kaplan-Meier estimator was used to estimate the survival ratio and Logistic ression was conducted.Results The median survival time was 22 months in all of the patients （95% confidence interval, 16.46-27.54）.The 3-and 5-year survival rates were 31.3% and 9.4%. FIGO staging was the risk factor of disease-free survival.Conclusions The prognosis of patients with cervical cancer complicated with syphilis is very Poor.It is very important to diagnose the disease early and to conduct standard comprehensive therapy.