期刊文献+

三维能量多普勒对前列腺癌分化程度研究

Study on differentiation of prostatic carcinoma diagnosed by three - dimensional power Doppler
下载PDF
导出
摘要 目的 探讨三维能量多普勒在诊断前列腺癌及其分化程度方面的临床价值.方法 回顾性分析经直肠三维能量多普勒检查68个前列腺肿块血流特征,并与病理结果对照分析.结果 前列腺良恶性肿块的血管指数(VI)差异有统计学意义(t=4.654,P=0.000).以VI>0.21条/cm^3诊断前列腺癌的灵敏度77.8%、特异度65.2%.高、中、低分化组的前列腺癌肿血管指数分别为0.0975±0.0680、0.1811±0.0977、0.2588±0.0577,组间差异有显著性(P<0.000).结论 经直肠三维能量多普勒检查为前列腺癌诊断提供了新的途径和方法,并能协助诊断前列腺癌的分化程度. Objective To evaluate the clinical diagnosing value in the differentiation of prostatic carcinoma by three - dimensional power Doppler. Methods The characteristics of blood flow examined by three - dimensional power Doppler were analyzed retrospectively and compared pathologically in 68 prostatic lesion. Results Vascularity index was significant differences between prostatic benign and malignant lesion ( t = 4. 654, P = 0.000). Using VI, the sensitivity and specificity were 77.8% and 65.2% respectively in diagnosing prostatic carcinoma. VI in well, moderate, poorly differentiated prostatic carcinoma was 0. 0975 ± 0. 0680,0. 1811 ±0. 0977 and 0. 2588 ±0. 0577, respectively, and there were significant differences among groups ( P 〈 0. 000 ). Conclusions Three -dimensional power Doppler offers a new way in diagnosis of prostatic carcinoma, and is helpful to the differentiation of prostatic carcinoma.
出处 《实用肿瘤学杂志》 CAS 2010年第5期413-414,438,共3页 Practical Oncology Journal
关键词 三维能量多普勒 经直肠超声 前列腺癌 病理学 分化 Three - dimensional power Doppler Transrectal ultrasound Prostatic carcinoma Pathology Differentiation
  • 相关文献

参考文献6

二级参考文献16

  • 1王广有,马腾骧.前列腺癌的诊断与临床分期[J].中华泌尿外科杂志,1995,16(2):102-104. 被引量:23
  • 2Mettlin C, Lee F, Grago J, Murphy GP. The American Cancer Society National Prostate Cancer Detection Group. Findings on the detection of early prostate cancer in 2425 men. Cancer 1991;67:2949~58.
  • 3Sauvain JL, Palascak P, Bremon JM. Power Doppler ultrasonography and hypoechoic nodules of the peripheral prostate: perspectives and limitations. J Radiol, 1997;78:491~7.
  • 4Bree RL. The role of color Doppler and staging biopsies in prostate cancer detection. Urology, 1997;49(3):31~4.
  • 5Okinhara K, Watanabe H, Kojima M. Kinetic study of blood flow in prostatic cancer using power Doppler imaging. Ultrasound Med Biol, 1999;25:89~94.
  • 6Shigeno K,Igawa M,Shiina H,et al.Transrectal colour Doppler ultrasonography for quantifying angiogenesis in prostate cancer.BJU Int,2003,91(3):223-226.
  • 7Bono AV,Celato N,Cova V,et al.Microvessel density in prostate carcinoma. Prostate-Cancer-Prostatic-Dis.2002,5(2):123-127.
  • 8Krupski T,Harding MA,Herce ME,et al.The role of vascular endothelial growth factor in the tissue specific in vivo growth of prostate cancer cells.Growth-Factors.2001,18(4):287-302.
  • 9Melnyk O,Zimmeman M,Kim Kj,et al.Neutralizing antivascular endothelial growth factor antibody inhibits further growth of established prostate cancer and metastases in a preclimical model.J Urol,1999,161(3):960-966.
  • 10Walsh K,Sriprasad S, Hopster D,et al.Distribution of vascular endothelial growth factor (VEGF) in prostate disease.Prostate-Cancer-Prostatic-Dis.2002,5(2):119-122.

共引文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部