胃癌高、低发区饮用水有机污染及致突变性研究

A Study on Organic Contamination and Mutagenicity of DrinkingWater in the area with High and Low Incidence of Gastric Cancer.

本文采用蚕豆根尖细胞微核（ＭＣＮ）、耗氧量（ＣＯＤ）对胃癌高、低发区饮用水水质进行监测，结果表明高发区地表水两项指标均明显高于地下水，也高于低发区地表水（Ｐ＜０．０５）。大型自来水厂的出厂水的诱变活性明显低于水源水（Ｐ＜０．０５），不同饮用水的ＣＯＤ、ＭＣＮ与胃癌死亡率有较好的一致性，提示饮水污染可能是致胃癌高发的因素之一。

This paper reports drinking water quality in the area with high incidence of gastric cancer(Changle county) compareing with one of the low area(sha county),using the micronucleus test in vacia faba root tips(MCN) and COD. Both MCN and COD. were higher in the surface water source in Changle county than that in sha county ( P<005) .There is a significantly decrease of two indexes in the treated water of water plant( P<005) .No change was observed on the MCN in small water plant. It suggests that organic and mutagenic pollution is more serious in the high risk area, Both COD and MCN have a closer relation with gastric cancer mortality The results indicate that the drinking water polution might be one of the causes for hicgh incidence of gastoic cancer.