264例牙源性肿瘤的临床特点与预后分析

Analysis of Clinical Characteristics and Prognosis of 264 Odontogenic Tumor Patients

[目的]分析牙源性肿瘤的临床病理与预后.[方法]对本院264例牙源性肿瘤患者临床资料中的发病部位、类型、病程、症状以及其中成釉细胞瘤的临床病理特点、术后复发率与手术之间的关系进行统计分析.[结果]264例患者（男∶女为1.3∶1）高发年龄段为10～39岁（67.8%）.其中20～29岁年龄段患者最多（26.5%）;病变病程在1.5年以内147例（55.7%）;绝大多数位于下颌骨（203例,76.9%）;最常见的是成釉细胞瘤（AME,152例, 57.6%）,颌骨阶段性或全切术的术后复发率为8.3%,明显低于刮治术的35.7%与箱状切除术的23.1%;促结缔组织增生型成釉细胞瘤（DA）15例,其术后复发率为13.3%,与137例非DA的16.1%相比,无统计学差异（P＞0.05）.[结论]牙源性肿瘤中成釉细胞瘤最为常见,且好发于下颌骨;颌骨阶段性或全切术的术后复发率较低;对DA的治疗仍应等同于其他类型AME.

[Objeetive] To analyze the clinical pathology and prognosis of odontogenic tumor. [Methods]Clinical data of 264 cases of odontogenic tumor were analyzed. The disease position, type, course, symptoms of odontogenic tumor and the clinicopathologic features of ameloblastoma and the relationship between the recurrence rate and operation were statistically analyzed. [Results] The age with high incidence of the disease was 10-39 years old （67.8%）, and the age with the highest incidence was 20-29 years old（26.5%）. The course of 147 cases（55.7%） was within 1.5 years. The most diseases（203 cases, 76.9%） located under the mandible; The most common type was ameloblastoma（152 cases, 57. 6%）. The recurrence rate after jaw digestion operation was 8.3%, which was obviously lower than that after the curettage（35.7%） and boxing resection operation（23.1%）. Fifteen cases were desmoplastic ameloblastoma（DA）, and its recurrence rate was 13.3%, which had no statistical difference with that of 137 cases of non-DA（16.1%）（ P 〉0.05）. [Conclusion] The ameloblastoma is the most common in odontogenic tumor and often occurs in the mandible. The recurrence rate of jaw digestion operation is relatively low. The treatment, of DA should be the same with other type of ameloblastoma.