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帕瑞昔布钠治疗全麻苏醒期躁动临床疗效观察

Clinical Effect Observation on Parecoxib Sodium Treating Emergence Agitation
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摘要 目的研究帕瑞昔布钠治疗全麻苏醒期躁动的临床疗效。方法 80例择期行腹腔镜胆囊切除术患者,随机分为A(帕瑞昔布钠组)和B(对照组)2组,在术毕缝皮前停用麻醉维持药,A组予帕瑞昔布钠40mg静脉注射(用生理盐水稀释至10mL),B组给予等量生理盐水;术后行烦躁等不良反应的观察。结果 A组术后烦躁的发生率显著低于B组,苏醒时间无明显差异。结论帕瑞昔布钠能减少腹腔镜胆囊切除术的术后烦躁。 Objective To assess clinical effect of parecoxib sodium on patients of emergence agitation.Methods 80 patients undergoing LC were classified into treatment group(parecoxib sodium)and control group(physiological saline).Observe and compare the emergence agitation of each group after treatment.Extubation time,recovery quality and PONC were also analyzed.Results The total effective rate was 95.1% in the treatment group,compared with 61.5% in the control group,The difference was significant(P0.05),proving that the efficacy of treatment is better in the treatment group than that in control group.Conclusion Parecoxib sodium is effective in the treatment of emergence agitation.
出处 《中外医疗》 2010年第29期9-9,11,共2页 China & Foreign Medical Treatment
关键词 帕瑞昔布钠 全身麻醉 躁动 Parecoxib sodium Genaral anesthesia Emergence agitation
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参考文献3

  • 1张桂华,马宪云,郭丽.全麻病人恢复期烦躁不安的原因分析及护理[J].哈尔滨医药,2002,22(3):91-92. 被引量:5
  • 2LalloyJJ,SertenshasSR,BrownDL,et al.N-{[(5-methyl-3-phenylisoxazol-4-yl)-phenyl] sulfonyl} propanemide sodium salt.Parecoxib sodium:A potent and selective inhibitor of COX-2 for parenteral administration[J].J Med Chem,2000,43:1661-1668.
  • 34Schug SA,Joshi GP,Camo F,et al.Cardiovascular safety of the cyclooxygenase-2selective inhibitors parecoxib and vaidecoxib in the postoperative setting:an analysis of intergrayed data[J].Anesth Analg,2009,103(1):299 - 307.

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