鲍曼不动杆菌临床感染及药敏试验结果分析

Analysis of the clinical infections and bacterial resistance of acinetobacter baumannii

目的分析医院鲍曼不动杆菌的临床分布及耐药性,以指导临床合理用药。方法对医院近2年分离出的鲍曼不动杆菌的临床分布特点及耐药情况进行总结分析。结果 2008年1月至2009年12月共分离出鲍曼不动杆菌791株,菌株来源主要为痰液、分泌物,分别占60.81%和11.76%;菌株分布于多个病区;鲍曼不动杆菌对头孢哌酮/舒巴坦(舒普深)、米诺环素和亚胺培南的敏感性较高。结论鲍曼不动杆菌主要引起下呼吸道感染;对氨苄西林和呋喃妥因及头孢菌素的耐药率高,呈多重耐药,头孢哌酮/舒巴坦(舒普深)和亚胺培南可作为治疗鲍曼不动杆菌严重感染者的首选用药。

Objective To investigate the distribution and antimicrobial resistance of infections caused by Acinetobacer baumannii in our hospital,for the guidence of the clinical application of antibiotics reasonably.Methods Retrospective analysis of the drug resistance situation and specimen distribution was made to the A.baumannii isolated from our hospital in the recent 2 years.Results Totally 791 strains of A.baumannii were isolated from Jan.2008 to Nov.2009,and the percentages of these strains isolated from sputum and secretions,were 60.81%and 11.76%,respectively;791strains of A.baumannii were distributed in many wards,which was more sensitive to Ceperazone/ Sul,Minocycline and Imipenem.Conclusion A.baumannii will mainly causes infections of respiratory tract in clinic.A.bauma-nnii is multidrug resistant and severely resistant to ampicillin,nitrofurantoin and cepho-losporins,ceperazone/sul and imipenem remains to be the first choice in treating the severe infection caused by A.baumannii.