子宫内膜癌合并多原发性癌20例临床研究

A clinical study of 20 cases of endometrial carcinoma associated with multiple primary carcinoma

目的：提高对子宫内膜癌合并多原发性癌的临床特点的认识。方法：对20例子宫内膜癌合并多原发性癌的临床资料进行回顾性分析。结果：子宫内股癌合并多原发性癌占同期子宫内膜癌的10．9％，其中合并卵巢恶性肿瘤最多见，占50％（10／20），合并乳腺癌、结／直肠癌者各4例（20％），合并膀胱癌、舌癌各1例。3例多原发性癌发生于子宫内股癌治疗后，6例发生于治疗前，11例同期发生。异期原发癌平均发病间隔时间54个月。结论；子宫内膜癌合并多原发性癌多见于50岁以上患者，生殖系统为其好发部位。

Objective: To improve the understanding of clinical manifestation of endometrial carcinoma (EC)associated with multiple primary carcinoma (MPC). Method: 20 cases diagnosed EC associated with MPC were analyzed by retrospective study Results: 10. 9% of patients suffered from EC were found to have developed MPC, ofwhich the EC with ovarian malignant tumors were the most common (50%, 10/20). The number of patients whoseMPC occurred in breast, colon or rectum, bladder and tongue was 4, 4, 1 and 1 respectively. 3 cases of MPC occuredafter the treatment of EC, 6 developed before treatment and 11 happened simultaneously. The average interval between EC and MPC was 54 months. Conclusion: Patients suffered from EC associated with MPC were often over 50ages. The common site for MPC was female reproductive system.