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生殖器疱疹复发与精神抑郁的相关性探讨 被引量:2

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摘要 目的探讨抑郁症状与复发性生殖器疱疹发病的相关性。方法随机选择90例复发性殖器疱疹患者和健康体检者,分为3组:A组28例,复发性生殖器疱疹患者复发频率>6次/年;B组30例,复发性生殖器疱疹患者复发频率≤6次/年,C组为健康对照组32例。分别别用抑郁自评量表(SDS)、汉米顿抑郁量表(HAMD)进行症状量化评分检测,评定入组前2周的精神心理状态,将3组的量表得分进行比较。结果 SDS评分、HAMD评分、抑郁发生率3组间的比较,A组均高于B、C两组,B组高于C组,3组间的差异有显著性(P<0.01)。结论抑郁症状与复发性生殖器疱疹有相关性,可能为复发性生殖器疱疹的危险因素之一。
出处 《中国医学创新》 CAS 2010年第27期44-45,共2页 Medical Innovation of China
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  • 1Silver SP,Averbach SM,Vishniavsky N,Kaplowitz LG.Psychological factors in recurrent genital herpes infection:stress,coping style,social support,emotional dysfunctionand symptom recurrence.J Psychosom Res,1986,30:163-171.
  • 2Longo D,Koehn K.Psychosocial factors and recurrent genital herpes:a reviewof prediction and psychiatric treatment studies.Int J Psychiatry Med,1993,23:99-117.
  • 3Uuskula A,Nygard-Kibur M,Cowan FM,et al.The burden of infection with herpes simp lex virus type 1 and type 2:seroprevalence study in Estonia.Scand J Infect Dis,2004,36 (10):727-732.
  • 4Bryson Y,Dillon M,Bernstein DI,et al.Risk of acquisition of genital herpes simplex virus type 2 in sex partners of persons with genital herpes:a prospective couple study.J Infect Dis,1993,167:942-946.
  • 5Poliak S,Mor F,Conlon P,et al.Stress and autoimmunity:the neuropeptides corticotropin-releasing factor and urocortin suppress encephalomyelitis via effects on both the hypothalamic-pituitary-adrenal axis and the immune system.J Immunol,1997,158:5751-5756.
  • 6Dhabhar FS.Acute stress enhances while chronic stress suppresses skin immunity.The role of stress hormones and leukocyte trafficking.Ann NY Acad Sci,2000,917:876-893.
  • 7臧运书,孙秀芳,臧传芳.复发性生殖器疱疹患者的抑郁情绪和细胞免疫功能的研究[J].中国艾滋病性病,2008,14(5):498-500. 被引量:2
  • 8Glaser R,MacCallum RC,Laskowski BF,et al.Evidence for a shift in the Th 1 to Th 2 cytokine response associated with chronic stress and aging.J Gerontol A Biol Sci Med Sci,2001,56(3):477-478.
  • 9Ashcraft KA,Hunzeker J,Bonneau RH.Psychological stress impairs the local CD8+ T cell response to mucosal HSV-1 infection and allows for increased pathogenicity via a glucocorticoid receptor-mediated mechanism.Psychoneuroendocrinology,2008,33(7):951-63.
  • 10Alexander L,Naisbett B.Patient and physician partnerships in managing genital herpes.J Infect Dis,2002,186 (Supp 1):57-65.

二级参考文献5

  • 1汪向东 王希林 马弘 等.心理卫生评定量表手册[M] 增订版[M].北京:中国心理卫生杂志社,1999.35-45.
  • 2Benedetti J, Corey 1, Ashley R. Recurrence rates in genital herpes after symptomatic first-epsode infection [J ] .Ann Intern Med, 1994, 121 (11) :847 - 854.
  • 3Neises M, Nebe T, Schiller A, et al. Coping with illness/quality of life and immunologic parameters of patients with breast carcinoma and benign tumors[ J ]. Gynkol Geburtshilfliche Rundseh, 1995,35 (Supp 1) : 166- 171.
  • 4Song C, Kenis G, van Gastel A, et al. Influence of psychological stress on immune-inflammatory variables in normal humans. Part Ⅱ . Altered serum concentrations of natural anti-inflammatory agents,and soluble membrane antigens of monocytes and T lymphoeytes [ J ] . Psychiatry Res, 1999,85:293 - 303.
  • 5伍志臻,陈福国,陈秀琴.五项细胞免疫指标与抑郁性神经症的相关性研究[J].上海医学检验杂志,1999,14(5):280-281. 被引量:13

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