尿道膀胱反流的临床研究

Urethro-vesical Reflux

目的探讨人体是否存在尿道膀胱反流及其临床意义。方法首次应用同位素检查方法对９例反复下尿路感染患儿和正常对照组３例儿童进行研究。结果证实人体中尿道膀胱反流（ＵＶＲ）的存在。结论尿道器质或功能性异常所引起的尿流改变及尿道外括约肌（ＥＵＳ）异常收缩是产生ＵＶＲ的重要机制。ＵＶＥ不但能诱发尿道感染（ＵＴＩ），并且是ＵＴＩ迁延不愈的重要因素。

Objective The study aims to evaluate if urethro-vesical reflux occur in children. MethodNine children with recurrent urinary tract infection underwent imaging study by 99m technetium-labeledsulfur colloid. The image was captured with GCA-90lA digital gamma camera system and processed withGMS-5u computer system. Results Urinary tract abnormality and spasm of external urethral sphinctermay lead to urethro-vesical reflux. Conclusions Urethro-vesical reflux in turn contributes to urinary tractinfection and a protracted course.