癌胚抗原测定对良性恶性心包积液鉴别的临床分析

Clinical analysis of detecting CEA in differentiating benign and malignant pericardial effusion

目的：对良性恶性心包积液作癌胚抗原（ＣＥＡ）水平测定。方法：采用放射免疫分析法，设定阳性值为ＣＥＡ＞２０ｍｇ／ｍｌ，各组间阳性率统计检验采用卡方检验。结果：恶性心包积液患者心包液的ＣＥＡ水平明显高于良性心包炎患者（Ｐ＜０．００１），不同类型的恶性心包积液ＣＥＡ检测结果有明显差异。结论：心包液ＣＥＡ测定对良性恶性心包积液的鉴别有一定的临床意义。

Objective:To evaluate the significance of detecting CEA of pericardial effusion in differentiating benign and malignant pericardial effusionMethod:CEA of pericardial effusion was detected by radioimmunoassayIt was determined as a positive result when CEA reached or more than the value of 20mg/LStatistical analysis of result was practiced by 2 testResult:CEA of pericardial effusion in patients with malignant pericardial effusion was much higher than that of tuberculosis pericardial effusion(P<0001)There were significantly differences in CEA in patients with malignant pericardial effusion,who were diagnosed by pathologyConclusion:Detection of CEA of pericardial effusion might be helpful for differentiating benign and malignant pericardial effusion