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血管性认知障碍非痴呆患者事件相关电位-P300的特点 被引量:4

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摘要 目的探讨血管性认知障碍非痴呆(VC IND)患者的听觉事件相关电位(ERP)-P300特点及其临床意义。方法根据MoCA评分将120例VC IND患者分为两组,22-26分为A组,18-21分为B组。另择健康体检者60例作为对照组。分别对其进行听觉ERP-P300检测。结果与对照组相比,A组P300潜伏期、N200-P300波间期延长,P300波幅减低;B组N200、P300潜伏期,P200-N200、N200-P300波间期明显延长,P300波幅减低(P〈0.05或〈0.01)。VC IND患者N200、P300潜伏期与性别无关,与MoCA分数呈负相关(r=-4.140、-0.895,P均〈0.01),P300潜伏期与年龄呈正相关(r=0.399,P=0.000)。结论 VC IND患者的ERP-P300特点为P300潜伏期、N200-P300波间期延长,P300波幅减低;ERP-P300对VC IND有一定的早期诊断价值。
机构地区 郑州人民医院
出处 《山东医药》 CAS 北大核心 2010年第41期40-41,共2页 Shandong Medical Journal
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参考文献6

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