原发性肝癌患者行^(131)I美妥昔单抗介入治疗的围术期护理

Perioperative Nursing of Hepatocellular Carcinoma Patients Undergoing 131I Rituximab Intervention Therapy

目的探讨原发性肝癌患者行131I美妥昔单抗介入治疗围术期的护理方法。方法回顾性分析2008年4-6月于某院行131I美妥昔单抗介入治疗的54例原发性肝癌患者临床资料。结果治疗后,54例患者的肿瘤均有不同程度的缩小。有27例患者发生不良反应,其中发热11例、恶心呕吐4例、肝区胀痛8例、便秘2例、腹泻1例、穿刺处出血1例。经对症处理后、,患者情况均好转,病情平稳;其余27例患者未发生术后不良反应。结论术前加强心理护理、健康指导,完善术前准备;术后严密细致地观察患者病情变化,倾听患者主诉,并加以综合分析,及早处理不良反应,可提高患者的生活质量。

Objective To explore perioperative nursing methods of hepatocellular carcinoma（HCC） patients undergoing 131I rituximab intervention therapy.Methods The clinical data of the patients undergoing 131I rituximab intervention therapy from April to June 2008 were analyzed retrospectively.Results Of the 54 patients,27 patients were found with adverse reactions,including fever（n=11）,gas pain in hepatic region（n=8）,nausea or vomiting（n=4）,constipation（n=2）,diarrhea（n=3）,and bleeding on puncture site（n=1）.After symptomatic treatment,the patients＇ conditions were improved and stable.No adverse reaction was found in the rest 27 patients.Conclusion Perioperative preparation should be accomplished by enhancing psychological nursing and healthy guidance.Postoperative observation on the patients＇ conditions should focus on the chief complaints of patients to make a comprehensive analysis and early management of adverse reactions for better quality of life.