乳杆菌活菌胶囊联合保妇康栓治疗老年性阴道炎的疗效观察

Living Preparation of Lactobacillus in Combination of Baofukang Suppository for Senile Vaginitis

目的:观察乳杆菌活菌胶囊(定君生)联合保妇康栓治疗老年性阴道炎的疗效。方法:观察组104例老年性阴道炎患者使用保妇康栓1周后加用乳杆菌活菌胶囊治疗10天;对照组96例老年性阴道炎患者则单纯应用保妇康栓1周。两组均在停药后3～7d复查比较其治愈率、总有效率。两组治愈者均在停药90d复查,比较其复发率。结果:观察组治愈率为73.08%,总有效率为96.15%;对照组治愈率为63.54%,总有效率为91.67%,两组差异无统计学意义(P>0.05)。观察组复发率为0,对照组复发率为21.88%,两组差异有统计学意义(P<0.05)。结论:乳杆菌活菌胶囊联合保妇康栓治疗老年性阴道炎疗效显著,复发率低,值得临床推广。

OBJECTIVE：To evaluate the clinical efficacy of Living Preparation of Lactobacillus combined Baofukang Suppository for senile vaginitis.METHODS：104 senile vaginitis cases（observation group） were assigned to receive add-on Living Preparation of Lactobacillus for 10 days after 1-week treatment with Baofukang Suppository,and another 96 cases to receive Baofukang Suppository alone for 1 week.The cure rates and the total effective rates were compared between the two groups after drug withdrawal for 3 to 7 days,and the recurrence rates were compared after drug withdrawal for 90 days.RESULTS：There were no significant differences between the observation group and the control group with respect to the cure rate（73.08% vs.63.54%） and the total effective rate（96.15% vs.91.67%）（P 〉 0.05）.However,there were significant differences between the two groups in the recurrence rate（0% vs.21.88%）（P 〈 0.05）.CONCLUSION：Treatment of senile vaginitis with Living Preparation of Lactobacillus combined Baofukang Suppository is more effective with lower recurrence rate compared with Baofukang Suppository alone,hence the combination therapy is worthy of being recommended in clinical practice.