血清脂蛋白a水平与老年性心血管疾病相关性探讨

To explore the correlation between serum Lipoprotein (a) level and senile cardiovascular disease

目的:探讨血清脂蛋白a[LP(a)]水平在老年性高血压、老年性急性心肌梗死(AMI)和老年性高脂血症中的诊断价值。方法:采用免疫透射比浊法检测老年人血清LP(a)的含量,其中高血压组60例、AMI组40例、高脂血症组30例,与对照组50例健康体检者相比较。结果:AMI组和高血压组的LP(a)水平与健康对照组比较差异有统计学意义(P<0.01),高脂血症组与健康对照组比较差异亦有统计学意义(P<0.05)。结论:老年人血清LP(a)水平与老年性高血压、AMI及高脂血症密切相关,是老年人心血管疾病诊断的一个重要指标,作为心血管疾病的独立危险因子,临床上应重视其检测。

Objective：To explore diagnostic value of serum lipoprotein（a） level in senile hypertension,acute myocardial infarction（AMI） and hyperlipemia.Methods：Serum LP（a） was detected by immunity transmission turbidimetric method.60 cases of hypertension,40 cases of AMI and 30 cases of hyperlipemia were used as study group,while 50 cases from healthy physical examination were used control group.Results： Deference among AMI group,hypertension group and control group was statistically significant in serum LP（a）（P〈0.01）.Similarly,there also had deference between hyperlipemia group and control group（P〈0.05）.Conclusions： The level of serum LP（a） is closely associated with hypertension,AMI and hyperlipemia,which is an important marker in senile cardiovascular disease diagnosis.LP（a） is regarded as an independent risk factor of cardiovascular disease,so more attention should be paid in clinic.