90例脑卒中后抑郁临床研究

90 cases of clinical study of post-stroke depression

目的:探讨脑卒中后抑郁(PSD)的发生机制及相关因素。方法:对90例脑卒中(卒中组)和68例糖尿病(对照组)患者用汉密尔顿抑郁量表(HAMD)调查抑郁的发生情况及临床特点。结果:脑卒中组的抑郁发生率(57.78%)明显高于对照组(8.82%)(P(0.01)。日常生活能力评定(ALD)量表,抑郁患者(79±4.5),非抑郁患者(85±6.2)(P(0.01)。欧洲脑卒中评分(ESS)标准,抑郁组(62.05±4.3),非抑郁组(69.20±9.8)(P(0.01)。伴言语困难者抑郁发生率(88.24%)明显高于不伴言语困难者(50.5%)(P(0.05)。结论:PSD的发生与日常活动能力(ADL)依赖程度及神经功能缺损严重程度有关,伴言语困难者抑郁发生率显著升高。

Objective：To study the mechanism and related factors of post-stroke depression（PSD）.Methods：Investigate the occurrence and clinical features of depression with a Hamilton depression scale（HAMD）between 90 patients with stroke（stroke group） and 68 patients with diabetes（control group）.Results： The incidence of post-stroke depression（57.78%） was significantly higher than The control group（8.82﹪）（P〈0.01）.Activities of daily living rating（ALD）scales showed that patients with depression is 79±4.5 and non-depressed patients is 85±6.2（P〈0.01）.The European stroke scale（ESS）standard display that depression group is 62.05±4.3 and non-depressed group is 69.20±9.8（P〈0.01）.The incidence of depression of Associated with speech difficulties（88.24%）is significantly higher than the unassociated with speech difficulties（50.5%）.（P〈0.05）.Conclusions： The incidence of post-stroke depression is related to Dependence on daily activities and Degree of neurological deficits.The incidence of depression of Associated with speech difficulties was significantly higher.