新疆墨玉县农村维吾尔族成人肾功能下降的患病率和相关危险因素研究

Epidemiologic study of reduced renal function among Uygur adults in Moyu rural area of Xinjiang

目的探索在新疆南疆农村维吾尔族聚集地开展慢性肾脏病(CKD)流行病学研究的方法,同时了解墨玉县农村维吾尔族成人肾功能下降的患病率及相关危险因素。方法在预调查的基础上采用分层容量随机抽样方法从墨玉县364个村抽取18岁以上维吾尔族成人1650人,进行问卷调查、慢性肾损伤指标检测和相关危险因素调查。结果在资料完整的1552名维吾尔族成人中,肾功能下降的患病率为1.4%,经年龄性别标化后的患病率为1.44%(95%CI为1.39%～1.49%)。多因素Logistic回归提示高血压、老龄、蛋白尿、高尿酸血症、脑卒中为肾功能下降的独立危险因素。结论墨玉县农村维吾尔族成人肾功能下降患病率为1.4%,相关危险因素为高血压、老龄、蛋白尿、高尿酸血症和脑卒中。

Objective To investigate the prevalence of reduced renal function and associated factors in a village of MoYu province in Xinjiang Uygur Autonomous Region.Methods One thousand six hundred and fifty residents（older than 18years）from 15villages in 364countries of MoYu coutry were randomly selected using a stratified,multistage sampling.Residents were received questionnaire survey,tested damage index of kidney and associated factors.Results After age and gender adjustment,the prevalence of reduced renal function was 1.44%（95%CI was 1.39～1.49%）.Systolic blood pressure,and elder age,albuminuria,Hyperuricemia,apoplexy were independently correlated with reduced renal function.Conclution In the underdeveloped area in MoYu country,the prevalence of reduced renal function was 1.44%,associated risk factors are systolic blood pressure,and elder age,albuminuria,Hyperuricemia,apoplexy.